Disease link between hsa-let-7a and colorectal cancer.
miRNA ID (from miR2Disease)hsa-let-7a-1
Expressiondown-regulated
MethodNorthern blot, qRT-PCR etc
Descriptionlet-7 low-expressing DLD-1 human colon cancer cells were transfected with let-7a-1 precursor miRNA, the cells underwent significant growth suppression. At that time, the levels of RAS and c-myc proteins were lowered after the transfection, whereas the levels of both of their mRNAs remained almost unchanged.
Reference (Pubmed ID)16651716
Year2006
GenesRAS,c-myc
CausalCausal
Plugin based on data from miR2Disease.