Disease link between hsa-let-7a and lung cancer.
miRNA ID (from miR2Disease)hsa-let-7a
Expressiondown-regulated
MethodNorthern blot, qRT-PCR etc
DescriptionOverexpression of let-7 in lung cancer cell lines alters cell cycle progression and reduces cell division.multiple genes involved in cell cycle and cell division functions are also directly or indirectly repressed by let-7.
Reference (Pubmed ID)17699775
Year2007
GenesCDK6, CDC25A
CausalCausal
Plugin based on data from miR2Disease.