Disease link between hsa-let-7a and acute promyelocytic leukemia (APL).
miRNA ID (from miR2Disease)hsa-let-7a-3
Expressionup-regulated
MethodNorthern blot, qRT-PCR etc
DescriptionUpregulation of miR-15a,miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223,miR-342 and miR-107, whereas miR-181b was downregulated in in acute promyelocytic leukemia patients and cell lines during all-trans-retinoic acid (ATRA) treatment.
Reference (Pubmed ID)17260024
Year2007
GenesBCL2, RAS
CausalCausal
Plugin based on data from miR2Disease.